Eli Lilly CEO on Covid antibody treatment's effectiveness against mutations

Eli Lilly CEO David Ricks says pre-clinical data that suggests the company's antibody treatment will be effective against the coronavirus variant found in the United Kingdom. He does say there is some concern that the treatment will not be as effective against the Japanese strain of the virus. For access to live and exclusive video from CNBC subscribe to CNBC PRO: cnb.cx/2NGeIvi
Eli Lilly Chairman and CEO Dave Ricks told CNBC on Tuesday he expects the company’s Covid-19 antibody drug to be effective against the coronavirus variant found in the U.K.
However, he said the strain found in South Africa likely presents greater challenges.
“The South African variant ... is the one of concern. It has more dramatic mutations to that spike protein, which is the target” of these antibody drugs, Ricks said on “Squawk Box.” “Theoretically, it could evade our medicines.”
Eli Lilly’s antibody drug received emergency use authorization from the U.S. Food and Drug Administration in November. The drug is targeted toward people who are recently diagnosed with Covid-19, with the hopes of preventing the need for hospitalization. Regeneron’s Covid-19 antibody treatment, which President Donald Trump received after contracting the disease, also has received limited clearance from the FDA.
Ricks said Eli Lilly wants to work with the FDA to be able to quickly test different versions of antibodies to see whether they would be effective against virus variants such as the one found in South Africa.
“We actually have a large library of these antibodies now that are sitting pre-clinically,” said Ricks. “We could think about a very expedited path to study them in maybe a month or two, and then authorize their use. That would seem to be a smart thing to do as this virus mutates.”
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评论 

  1. HeartDoc Andrew

    HeartDoc Andrew

    5 天 前

    "Eli Lilly CEO on Covid antibody treatment's effectiveness against mutations" motivates us, the people of America, to redouble our efforts to rapidly find out at any given moment, including even while On-Line, who among us are unwittingly contagious (i.e. pre-symptomatic or asymptomatic) in order to #ConvinceItForward for them to call their doctor and to self-quarantine per CDC guidelines in hopes of stopping this pandemic instead of having more #MourningInAmerica (per #LincolnProject) even for the worse-case scenario of the #UKvariant strain(s) mutations and others like the South African & #Cluster5Mink mutations rendering current vaccines no longer effective.

  2. EgCh

    EgCh

    5 天 前

    Pandemic has led us into crypto revolution. People are participating and using crypto silently as part of the social movement in changing the status quo, and exiting the current system to avoid the outrageous and endless money-printing in which the government has stolen purchasing power indirectly from everyone over the years, not to mention they colluded with the private conglomerates to de-platform people from the social media(s) who are outspoken and have different ideologies from them. At this turbulent time, people are looking for a safe heaven, one of it is the Bitcoin. Bitcoin is being bought at the moment to hedge against the inflation, global uncertainties, loss of jobs and unwise monetary policies taken by the governments across the world while also provide a counter check and balance to the existing centralized nature of private entities who enrich themselves and enslave others. Protests and dissents that we witnessed across the world are the result of the outrageous fiscal and monetary policies implemented by the irresponsible government. The current system was designed to enrich the very few person sitting on the top. The current system that has been running for over decades was financially re-engineered to enrich the elites that had created many unwanted social-economical issues. Apart from buying Bitcoin, another way to preserve the value of your money and participate in the crypto revolution as a way to protest silently against government' irresponsibility is also to look at longer horizon and invest in - 'decentralized' smart contract platform that would not be regarded as 'security' that may have legal implications ( For eample XRP and EOS would have legal implication due to its centralization nature ) - a decentralized/#Defi platform that has its utility token to support the network and run the decentralized applications. 1) Bitcoin is a decentralized community money but it was not designed to run decentralized application and Ethereum doesn't have limited supply - hence there is no scarcity in Ethereum, its appreciation may not be great in long run. 2) Cardano has limited supply and halving like Bitcoin and that it can be used to write better and more secured dApps / Defi app in its smart contract platform than Ethereum. Adding to that, Cardano is more decentralized than Ethereum and Bitcoin combined.You can almost say, Cardano = Bitcoin + Ethereum. You can watch it here why is that - cnwill.info/show/nqeUe4SogNmOoIQ/sh-p-n.html As utility token is not speculative in nature, hence its price can be more sustainable in long run with big potential upside due to the various decentralization applications that will be built and run on the top of the blockchain. When Defi and decentralization applications take off and have mass adoption in the coming years, Cardano is no longer an option but it's a security choice one has to make. We know any dapps that run on top of a smart platform would involve risk of dollar and cents, anyone who is technical sensible person would not want to build a decentralized application on Ethereum that its platform has been experimented on the go and still is. The gas fee(s) in Ethereum are costing people ridiculously an arm and leg now. You can also sense Ethereum' technical foundational layer is rather shaky and not to mention the number of security incidents in the past, that the Ethereum platform itself has opened up several vulnerabilities - dapps were hacked as result of its flaw, and you wouldn't know what comes out next and fall apart again. Many people argued Ethereum has the first mover advantage, but that would not be the reason people would consider in building useful and mission critical application on it, especially once the blockchain space get more mature and people can have a better grasp on the pros and cons of it and appreciate the security and scalability aspects of it are needed in decentralized application. The Ethereum fans can bend the reality as much as they want, but at the end of the day, they won't be able to change the fact that Cardano was designed on the outset for building mission critical applications with high-assurances on the security and scalability aspects. When one look at the progress on the protocol development over the last 2 years, IOHK was very assured on its technical protocol Quroboros which have the highest security assurances design among all the proof of stake protocol. Over the last 3 years they never once changed its stance on the protocol design approach and how its distribution mechanism should run at its foundation level, they only reuse the previous working protocol and iterate it in making it better. It shows at the technical foundational level, it has a very solid security design and they were very assured about it, unlike Ethereum2.0. If the security was one of the reasons why Institutional Investor put their money in bitcoin, then I can't see why the big investors would not choose Cardano over Ethereum in the coming 12 - 15 months. #Cardano #Ada'was built to provide equal footing and opportunities for everyone in sharing the pies of the digital economy. Its technical superiority, philosophical approaches and more importantly its well-knowledge/helpful communities are second to none in changing the world for the betterment of humanity. Cardano is about changing the world for millions of people, that can also mean bringing wealth to millions as well. The more people Cardano positively impacts, the more it will be used. Cardano's use case will be different for all of us. The speech recently from Cardano founder'- cnwill.info/show/iqzJapu1n61hnWc/sh-p-n.html

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